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トップページ » 貿易事業 » ライフケア » 食品・健康&美容商品» Probiotical プロバイオティカル イタリア 生菌剤の世界的メーカー(泌尿器系)

Probiotical プロバイオティカル - 多様な生菌剤の世界的メーカー

プロバイオティカル社の多様な菌株と領域別菌株

BIFIDOBACTERIUM STRAINS
ビフィズス菌株
消化器系 骨と髪の健康 神経系
LACTOBACILLUS STRAINS
乳酸菌株
免疫と
アレルギー
心血管代謝 アイケア
STREPTOCOCCUS THERMOPHILUS
連鎖球菌サーモフィルス
皮膚系 婦人系 スポーツ
BLENDS
ブレンド
健康な老化 泌尿器系 オーラルケア
   
泌尿器系

尿路感染(UTI)


Lactiplantibacillus plantarum LP01™ (LMG P-21021)
(旧名 Lactobacillus plantarum )
Lacticaseibacillus paracasei LPC09 (DSM 24243)
(旧名 Lactobacillus paracasei )
Streptococcus thermophilus ST10 (DSM 25246)
BIFICIST®
機能性
  • 膀胱炎
  • シュウ酸塩の代謝、腎臓結石の予防
  • 大腸菌の抑制
可能形態 ブレンド原体、あるいは製剤

学術サポート
 ヒト臨床試験
  1. Vicariotto F. Effectiveness of An Association of a Cranberry Dry Extract, D-Mannose, and the 2 Microorganisms Lactobacillus plantarum LP01 and Lactobacillus paracasei LPC09 in Women Affected by Cystitis. Journal of Clin Gastroenterol 2014;48:S96-S101.
 インビトロ研究
  1. Mogna L. et al. Assessment of the in vitro inhibitory activity of specific probiotic bacteria against different Escherichia coli strains. J Clin Gastroenterol. 2012; 46 Suppl:S29-32.
  2. Mogna L. et al. Screening of different probiotic strains for their in vitro ability to metabolise oxalates: any prospective use in humans? J Clin Gastroenterol. 2014; 48 Suppl:S91-95.
  3. Deidda F, et al. How Probiotics may Kill Harmful Bacteria: The in vitro Activity against Some Haemolytic Strains. J Prob Health, 2020. Vol. 8 Iss.2 No: 216.
  4. Amoruso A. et al. (2019) A Systematic Evaluation of the Immunomodulatory and Functional Properties of Probiotic Bifidobacterium Breve BR03 (DSM 16604) Lactobacillus plantarum LP01 (LMG P-21021). J Prob Health. 7:214.
 抗炎症作用と抗酸化作用に関する内部データはご要望により入手可能です。

Lactiplantibacillus plantarum LP01™ (LMG P-21021)
(旧名 Lactobacillus plantarum )
Lactiplantibacillus plantarum LP02 (LMG P-21020)
(旧名 Lactobacillus plantarum )
Lacticaseibacillus rhamnosus LR04 (DSM 16605)
(旧名 Lactobacillus rhamnosus )
Lacticaseibacillus rhamnosus LR06 (DSM 21981)
(旧名 Lactobacillus rhamnosus )
Lactiplantibacillus pentosus LPS01 (DSM 21980)
(旧名 Lactobacillus pentosus )
Bifidobacterium breve BR03™ (DSM 16604)

機能性
  • 膀胱炎
  • 大腸菌、フェカリス菌、肺炎桿菌の抑制
臨床試験における1日の投与量
 1) LP01 2.5 billion cells + LPC09 1 billion cells + ST10 1 billion cells + tara gum + cranberry extract + D-mannose
*("CFU"は非処理の菌数、"cell"はマイクロカプセル化菌数)
可能形態 単体原体、ブレンド原体、あるいは製剤

学術サポート
 インビトロ研究
  1. Mogna L. et al. Assessment of the in vitro inhibitory activity of specific probiotic bacteria against different Escherichia coli strains. J Clin Gastroenterol. 2012; 46 Suppl:S29-32.
  2. Deidda F, et al. How Probiotics may Kill Harmful Bacteria: The in vitro Activity against Some Haemolytic Strains. J Prob Health, 2020. Vol. 8 Iss.2 No: 216.
  3. Amoruso A. et al. (2019) A Systematic Evaluation of the Immunomodulatory and Functional Properties of Probiotic Bifidobacterium Breve BR03 (DSM 16604) Lactobacillus plantarum LP01 (LMG P-21021). J Prob Health. 7:214.
  4. Nicola S. et al. Interaction between probiotics and human immune cells: the prospective anti-inflammatory activity of Bifidobacterium breve BR03. AgroFOOD, 2010; 21(2):S44-47.
 これらの菌種の一部については、ご要望に応じて抗炎症作用と抗酸化作用に関する内部データを入手可能です。

Lactobacillus delbrueckii subsp. delbrueckii LDD01 (DSM 22106)

機能性
  • 病原体となる大腸菌、クレブシエラ菌およびガス発生性大腸菌群の抑制
可能形態 単体原体、ブレンド原体、あるいは製剤

学術サポート
 インビトロ研究
  1. Mogna L. et al. Assessment of the in vitro inhibitory activity of specific probiotic bacteria against different Escherichia coli strains. J Clin Gastroenterol. 2012; 46 Suppl:S29-32.
  2. Savino F. et al. Antagonistic effect of Lactobacillus strains against gasproducing coliforms isolated from colicky infants. BMC Microbiology 2011, 11:157.
  3. Mogna L. et al. In Vitro Inhibition of Klebsiella pneumoniae by Lactobacillus delbrueckii subsp. delbrueckii LDD01 (DSM 22106): An Innovative Strategy to Possibly Counteract Such Infections in Humans? J Clin Gastroenterol. 2016 Nov/Dec;50 Suppl 2, Proceedings from the 8th Probiotics, Prebiotics & New Foods for Microbiota and Human Health meeting held in Rome, Italy on September 13-15, 2015:S136-S139.

Bifidobacterium breve B632™(DSM 24706)

機能性
  • 病原体となる大腸菌、および腸内細菌科の抑制
可能形態 ブレンド原体、あるいは製剤

学術サポート
 インビトロ研究
  1. Mogna L. et al. Assessment of the in vitro inhibitory activity of specific probiotic bacteria against different Escherichia coli strains. J Clin Gastroenterol. 2012; 46 Suppl:S29-32.
  2. Simone M. et al. The Probiotic Bifidobacterium breve B632 Inhibited the Growth of Enterobacteriaceae within Colicky Infant Microbiota Cultures. BioMed Research International 1-6, 2014.

Ligilactobacillus salivarius CRL1328 (DSM 24441)
(旧名 Lactobacillus salivarius )


機能性
  • 泌尿生殖器感染症の予防
  • カンジダの抑制
  • 淋病
  • エンテロコッカス・フェカリス、エンテロコッカス・フェシウムおよびナイセリア菌の阻害
可能形態 単体原体、ブレンド原体、あるいは製剤

学術サポート
 インビトロ研究
  1. Ocana V. et al. Characterization of a bacteriocin like substance produced by a vaginal Lactobacillus salivarius strain. Applied and Environmental Microbiology, 1999; 65(12):5631-5635.
  2. Ocana V. et al. Surface characteristics of Lactobacilli isolated from human vagina. J. Gen. Appl. Microbiol., 1999; 45:203-212.
  3. Tomas MSJ. et al. Influence of pH, temperature and culture media on the growth and bacteriocin production by vaginal Lactobacillus salivarius CRL 1328. Journal of Applied Microbiology, 2002; 93: 714-724.
  4. Rovere F. Local tolerability and activity study in patients suffering from Candida albicans (Delmati2 Hospital, Italy, 1992).
  5. Gillor O. et al. The dual role of bacteriocins as anti- and probiotics. Appl Microbiol Biotechnol. 2008 December; 81(4): 591–606. doi: 10.1007/ s00253-008-1726-5.
  6. Dover S.E. et al. Natural antimicrobials and their role in vaginal health: a short review. Int J Probiotics Prebiotics. 2008 ; 3(4): 219–230.
  7. Juárez Tomás M.S. et al. Viability of vaginal probiotic Lactobacilli during refrigerated and frozen storage. Anaerobe, Vol 10, Issue 1, February 2004, 1-5.


前立腺の健康


Lactiplantibacillus plantarum LP01™ (LMG P-21021)
(旧名 Lactobacillus plantarum )
Lacticaseibacillus paracasei LPC09 (DSM 24243)
(旧名 Lactobacillus paracasei )
BIFIPROST®

機能性
  • 慢性細菌性前立腺炎の予防
  • シュウ酸塩の代謝、腎臓結石の予防
  • 抗炎症作用
  • 大腸菌の抑制
  • 尿路感染症
可能形態 単体原体、ブレンド原体、あるいは製剤

学術サポート
 ヒト臨床試験
  1. Chiancone F. et al. The Use of a Combination of Vaccinium Macracarpon, Lycium barbarum L. and Probiotics (Bifiprost®) for the Prevention of Chronic Bacterial Prostatitis: A Double-Blind Randomized Study. Urologia Internationalis 2019.
 インビトロ研究
  1. Mogna L. et al. Assessment of the in vitro inhibitory activity of specific probiotic bacteria against different Escherichia coli strains. J Clin Gastroenterol. 2012; 46 Suppl:S29-32.
  2. Deidda F, et al. How Probiotics may Kill Harmful Bacteria: The in vitro Activity against Some Haemolytic Strains. J Prob Health, 2020. Vol. 8 Iss.2 No: 216.
  3. Mogna L. et al. Screening of different probiotic strains for their in vitro ability to metabolise oxalates: any prospective use in humans? J Clin Gastroenterol. 2014; 48 Suppl:S91-95.
  4. Amoruso A. et al. (2019) A Systematic Evaluation of the Immunomodulatory and Functional Properties of Probiotic Bifidobacterium Breve BR03 (DSM 16604) Lactobacillus plantarum LP01 (LMG P-21021). J Prob Health. 7:214. Internal data on anti-inflammatory and anti-oxidant properties avai-lable upon request.
 抗炎症作用および抗酸化作用に関する内部データは、ご要望に応じて入手可能です。

Bifidobacterium animalis subsp. lactis Bb1 (DSM 17850)
Limosilactobacillus reuteri Lb26 (DSM 16341)
(旧名 Lactobacillus reuteri )

機能性
  • 高いバイオアヴェイラビリティのアレルゲンフリーのプロバイオティック株由来の有機亜鉛とセレン
  • 正常な認知機能
  • 正常な骨の維持
  • DNA、タンパク質、脂質を酸化損傷から保護
  • 正常なDNA合成と細胞分裂
  • 免疫系の正常な機能
可能形態 単体原体、ブレンド原体、あるいは製剤

学術サポート
 インビトロ研究
  1. Mogna L. et al. Selenium and zinc internalized by Lactobacillus buchneri Lb26 (DSM 16341) and Bifidobacterium lactis Bb1 (DSM 17850): improved bioavailability using a new biological approach. J Clin Gastroenterol. 2012; 46 Suppl:S41-5.
  2. Mangiapane E. et al. An integrated proteomic and physiological approach to understand the adhesion mechanism of the probiotic Lactobacillus reuteri Lb26 DSM16341. Journal of integrated Omics, 2013.
  3. Galano E. et al. Privileged Incorporation of Selenium as Selenocysteine in Lactobacillus reuteri Proteins Demonstrated by Selenium-specific Imaging and Proteomics. Molecular & Cellular Proteomics 12.8, 2013.
  4. Mangiapane E. et al. Selenium effects on the metabolism of a Semetabolizing Lactobacillus reuteri: analysis of envelope-enriched and extracellular proteomes. The Royal Society of Chemistry, 2014.
  5. Mangiapane E. et al. Selenium and Selenoproteins: An Overview on Different Biological Systems. Current Protein and Peptide Science, 2014, 15, 598-607.
 Lb26 の特性評価およびそのセレン代謝に関するさらなる研究は、ご要望に応じて利用可能です。


腎臓結石


Lacticaseibacillus paracasei LPC09 (DSM 24243)
(旧名 Lactobacillus paracasei )
可能形態 ブレンド原体、あるいは製剤

Lactobacillus acidophilus LA02 (DSM 21717)
Lactiplantibacillus plantarum LP01™ (LMG P-21021)
(旧名 Lactobacillus plantarum )
Limosilactobacillus reuteri LRE02 (DSM 23878)
(旧名 Lactobacillus reuteri )
Bifidobacterium animalis subsp. lactis Bb1 (DSM 17850)
Bifidobacterium breve BR03™ (DSM 16604)
Bifidobacterium longum BL03 (DSM 16603)
可能形態 単体原体、ブレンド原体、あるいは製剤

機能性
  • シュウ酸分解
  • 腎臓結石の発生率が減少する可能性
  • 腸の炎症の軽減

学術サポート
 インビトロ研究
  1. Mogna L. et al. Screening of different probiotic strains for their in vitro ability to metabolise oxalates: any prospective use in humans? (LPC09, LA02, LP01, LRE02, BR03, BL03) J Clin Gastroenterol. 2014; 48 Suppl:S91-95.
  2. Deidda F, et al. How Probiotics may Kill Harmful Bacteria: The in vitro Activity against Some Haemolytic Strains. J Prob Health, 2020. Vol. 8 Iss.2 No: 216.
  3. Amoruso A. et al. (2019) A Systematic Evaluation of the Immunomodulatory and Functional Properties of Probiotic Bifidobacterium Breve BR03 (DSM 16604) Lactobacillus plantarum LP01 (LMG P-21021). J Prob Health. 7:214.
  4. Nicola S. et al. Interaction between probiotics and human immune cells: the prospective anti-inflammatory activity of Bifidobacterium breve BR03. AgroFOOD, 2010; 21(2):S44-47.
  5. Mogna L. et al. Assessment of the in vitro inhibitory activity of specific probiotic bacteria against different Escherichia coli strains. J Clin Gastroenterol. 2012; 46 Suppl:S29-32.
 特定の菌株については、ご要望に応じて抗炎症および抗酸化特性に関する内部データが入手可能です。
採用情報

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